皮肤肥大细胞增生症的临床病理和误诊分析

Analysis of Clinicopathology and Misdiagnosis of Cutaneous Mastocytosis

目的 探讨皮肤肥大细胞增生症的临床病理特点及误诊原因。方法 回顾分析 35例皮肤肥大细胞增生症患者的临床表现和病理改变。结果 通过组织病理和 Giemsa染色协助诊断 ,35例全部确诊为皮肤肥大细胞增生症 ,其中有 13例在当地医院分别诊断为扁平苔藓、播散性黄色瘤、幼年黄色肉芽肿、持久性隆起性红斑、结节病、荨麻疹性血管炎、丘疹性荨麻疹、网状青斑和雀斑样痣等。结论 皮肤肥大细胞增生症临床表现复杂多样 ,易与多种其他皮肤病相混淆 ,诊断要结合皮损特点、病理组织学检查和

Objective To study the characteristic of clinicopathology and the causes of misdiagnosis of cutaneous mastocytosis.Methods 35 cases of cutaneous mastocytosis were retrospectively analysed.Results With the help of pathology and Giemsa stain,35 cases were finial diagnosed as cutaneous mastocytosis,among which there were 13 cases diagnosed as lichen planus,xanthoma disseminatum,juvenile xanthogranuloma,erythema elevatum diutinum,sarcoidosis,urticaria vasculitis,urticaria papulosa,livedo reticularis and lentigo.Conclusions Because of the complex clinical manifestation,cutaneous mastocytosis might be confused with other skin diseases.Its diagnosis should combined the characteristic of rash witht he result of biopsy and Giemsa stain.