紫菜多糖对免疫细胞及肿瘤细胞生长的影响(英文)

Effects of a Polysaccharide from Porphyra yezoensis on Murine Immunocytes and Human Leukemia K562 Cells

采用细胞培养技术测定从条斑紫菜中得到的多糖PY3对小鼠免疫细胞及人肿瘤细胞K5 6 2生长的影响 .结果表明 ,PY3对小鼠骨髓细胞和脾脏淋巴细胞的增殖以及对混合淋巴细胞反应均有一定的促进作用 .PY3对血癌细胞K5 6 2的生长有一定的抑制作用 .研究表明多糖PY3不仅能够提高小鼠免疫细胞的功能 ,而且有一定的抗肿瘤作用 .

Cell culture techniques were utilized to study the effects of the polysaccharide PY3 from Porphyra yezoensis on murine immunocytes and human tumor cell K562 in vitro. The proliferation of murine bone marrow cells, lymphocytes and the mixed lymphocyte reaction were detected when they were treated with PY3 of different concentrations. Its effects on human tumor cell K562 were explored in vitro as well. The results showed that PY3 could stimulate the proliferation of murine bone marrow cells and spleen cells, enhance the mixed lymphocyte reaction and inhibit the growth of K562 cells. The study suggests that the polysaccharide PY3 may not only improve the immunological function of mice, but also possess antitumor activity.