雌二醇对大鼠颌下腺EGF、NGF生成的影响

EFFECTS OF ESTRADIOL-17β ON THE SYNTHESIS OF EPIDERMAL GROWTH FACTOR AND NERVE GROWTH FACTOR IN SUBMANDIBULAR GLAND OF RAT

为了研究雌二醇 (estradiol- 17β,E2 )对颌下腺表皮生长因子 (epidermal growth factor,EGF)和神经生长因子(nerve growth factor,NGF)生成的影响 ,研究采用免疫组织化学方法 ,对外源性投予雌二醇后的大鼠颌下腺进行了观察。结果证实 E2 明显促进颌下腺 EGF和 NGF的生成。提示雌二醇可能对 EGF和

In order to study the effects of estradiol 17β(17β E 2) on the synthesis of EGF and NGF in submandibular gland of rat, which were adiministrited with exogenous 17β E 2 immunohistochemistry method was used. The results showed that 17β E 2 obviously promoted the synthesis of EGF and NGF in submandibular gland. This result suggested that 17β E 2 might play an important role in the synthesis of EGF and NGF.