赤芍注射液穴位注射加针刺对脑梗死患者PAG、PLT、MPV的影响

Clinical Observation on the Variations of PAG, PLT, MPV in Patients of Cerebral Infarction Treated by Acupoint Injection with Red Peong Root Liquor and Acupuncture

目的:探索赤芍注射液穴位注射加针刺治疗脑梗死的临床机理。方法:将120例经头颅CT扫描确诊为脑梗死的患者,随机分为观察组、对照组各60例,观察组给予赤芍注射液穴位注射加针刺治疗,对照组给予针刺治疗,观察治疗前后功能积分情况、血小板聚集功能(PAG)、血小板计数(PLT)、血小板平均体积(MPV)的变化。结果:脑梗死患者治疗前PAG亢进,PLT减少,MPV增大,且PAG与MPV呈正相关,治疗后,观察组及对照组均可调节上述指标,观察组优于对照组(P<0.05),观察组及对照组功能积分均较治疗前有极显著改善(P<0.01),观察组优于对照组(P<0.05)。结论:赤芍注射液穴位注射加针刺是治疗脑梗死的较好方法,调整PLT、MPV,抑制PAG是其活血化瘀、调整虚实的机理之一。

Objective:To probe into the clinical mechanism of acupoint injection with Red Peong Root Liqour and acupuncture. Methods:Definitely diagnosed by CT, 120 cases of cerebral infarction (CI) patients were divided randomly into the treatment group and the control group. The patients of the treatment group were treated by both acupoint injection with Red Peong Root Liqour and acupuncture, and the control group were treated by acupuncture. Functional scores and the variations of platelet aggreation(PAV), platelet numer(PLT), mean platelet volume(MPV) were observed before and after treated. Results:PAG, MPV increased obviously while PLT decreased, and PAG had a positive relation with MPV before treatment;treatment in the treatment group and control group could both regulate in the indexes, but the result in the treatment group was better than in the control group(P<0.05);the functional scores in both groups were decreased extremely obvious after the treatment(P<0.01), and the treatment group was superior to the control one(P<0.05). Conclusion:This research has suggested that treating CI by acupoint injection with Red Peong Root Liqour and acupuncture is a rather good therapeutic way, also suggested that regulating PLT, MPV and inhibiting PAG be one of the machanisms of “activating blood flow and removing blood stasis” and “regulating deficiency and excess”.