二甲基甲酰胺诱导艾氏腹水型癌细胞膜表面蛋白多糖的电镜观察

Electronic Microscopic Observation of Membrane Surface Proteoglycan of Mous Ehrlich Ascites Tumors Induced by Dimethyl Formamide

用 Ehrlich 腹水癌细胞为肿瘤模型,利用电镜细胞化学方法研究了二甲基甲酰胺对 Ehrlich 腹水癌细胞分化诱导作用,观察了癌细胞表面微绒毛及蛋白多糖的变化。结果表明,Ehrlich 腹水癌细胞在二甲基甲酰胺分化诱导下,细胞表面微绒毛减少或变短,同时细胞表面微绒毛区和非微绒毛区的蛋白多糖也有不同程度的减少。

The surface microvilli and proteoglycan of Ehrlich ascites tumor cells induced and differentiated by dimethyl formamide were studied-the model of Ehrlich ascites tumor cells by the method of electron- ic microscopic cytochemistry.The result shows that the surface microvilli of Ehrlich ascites turnor cells reduce and shorten.and that the proteoglycan on the surface microvilli as well as that on the membrane surface reduce.