4-羟基-5-取代苯基-3-吡唑烷酮类化合物的合成

Synthesis of 4-Hydroxy-5-substituted Phenyl-3-pyrazolidinones

根据改进的Topliss方法设计并合成了10个4-羟基-5-取代苯基-3-吡唑烷酮类衍生物,经抗惊药理实验证明其抗惊活性较低。

Ten derivatives of 4-hydroxy-5-substituted phenyl-3-pyrazolidinones were designed and synthesised by Topliss method, which possess week anticovulsant activity.