均匀设计用于优选芬氟拉明合成的工艺条件

Uniform Design Used in Optimization of Experimental Conditions in Synthesis of Fenfluramine

在合成芬氟拉明的工艺研究中,采用均匀设计方法安排试验,并通过微机运算求得定量方程,以此选择最后还原胺化反应的最佳工艺条件,使产率提高15％,获得了预期结果。

Using uniform design as an experimental design method, favorable result was obtained in the research of synthetic conditions of fenfluramine.