中草药添加剂对生长肥育猪免疫功能的影响研究

Effect of Chinese Herb Feed Additives on the Immune Function of Growing and Finishing Pigs

选用 2 0kg左右的“杜长大”三元杂交猪 12 0头 ,分成对照组、中药组、中药 +西药组 ,每组 4个重复 ,进行饲养试验。每期实验结束前 ,每组采集 8头猪血样 ,测定生长育肥猪血清中免疫球蛋白IgG ,IgA ,IgM和补体C3 ,C4的含量。结果表明 :在 2 0～ 30kg ,30～ 70kg和 70～ 110kg阶段 ,与对照组相比 ,中药组、中 +西组猪的血清IgG水平 ,分别提高了 2 3 75 % (P <0 0 5 )和 18 4 9% (P <0 0 5 ) ,17 6 6 % (P <0 0 5 )和 13 93% (P <0 0 5 ) ,14 79% (P <0 0 5 )和11 87% (P <0 0 5 ) ;IgM水平 ,分别提高了 2 5 0 4 % (P <0 0 5 )和 14 99% (P <0 0 5 ) ,2 2 81% (P <0 0 5 )和 15 18% (P<0 0 5 ) ,5 79% (P >0 0 5 )和 4 2 3% (P >0 0 5 ) ;IgA水平 ,分别提高了 9 71% (P >0 0 5 )和 0 5 7% (P >0 0 5 ) ,16 92 % (P <0 0 5 )和 7 6 0 % (P >0 0 5 ) ,15 0 1% (P <0 0 5 )和 7 2 3% (P >0 0 5 ) ;C3 水平 ,分别提高了 12 16 % (P <0 0 5 )和 14 19% (P <0 0 5 ) ,15 87% (P <0 0 5 )和 17 4 6 % (P <0 0 5 ) ,14 2 9% (P <0 0 5 )和 2 1 4 3% (P <0 0 5 ) ;C4水平 ,分别提高了 13 5 1% (P <0 0 5 ) ,5 0 2 % (P <0 0 5 ) ,6 6 7% (P <0 0 5 ) .研究结果提示 。

To investigate the effect of Chinese herb feed additives on the content of immunoglobulin(IgG, IgA, IgM) and complement(C 3,C 4) in the serum of growing and finishing pigs.120 growing and finishing pigs(Duroc×Landrace×Yorkshire,20?kg initially)were assigned into control and treated group set with four replicate pens per treatments by weight and sex. Fed basic diet supplemented with Chinese herb feed additives or antibiotic/chemical compound drug. The results showed that comparing to the control group ,the Chinese herb feed additives group and Chinese herb feed additives + antibiotic group , increased the content of IgG in serum of treated pigs by 23.75% and 18.49%, 17.66%and 13.93%,14.79% and 11.87% during the growing period of 20～30,30～70,70～110?kg respectively ( P <0.05);25.04%( P <0.05) and 14.99%( P <0.05), 22.81% (P<0.05)and 15.18%( P <0.05),5.79%( P >0.05) and 4.23%( P >0.05) for the content of IgM respectively;9.71%( P >0.05)and 0.57%( P >0.05),16.92%( P <0.05) and 7.60% ( P >0.05), 15.01% ( P <0.05) and 7.23% ( P >0.05) for the content of IgA respectively; 12.16% and 14.19%,15.87% and 17.46%,14.29% and 21.43% for the content of C 3 respectively( P <0.05);13.51%,5.02% and 6.67% for the content of C 4 respectively( P <0.05). These results indicated that the effect of Chinese herb feed additives on the function of body fluid immune in growing and finishing pigs not only improved the formation of immunoglobulin, but also ameliorate the formation of complement so that improved body's body fluid immune function.