摘要
本文对119例肝硬化和/或肝癌、24例正常肝组织作AFP、HBsAg、HBcAg免疫组化观察。结果表明:肝硬化和肝癌组其肝细胞不典型增生(LCD) 发生率显著高于非硬化者,同时在LCD中检出AFP,因而支持LCD为肝细胞癌的癌前病变;LCD的发生与乙型肝炎关系较大而与血吸虫感染无关。
Pathology and AFP, HBsAg, HBcAg immunohistochemistry were studied in 119 cases of cirrhosis and / or liver cell carcinoma (LCC) and 24 cases of otherwise normal liver.It was found that the occurence of liver cell dysplasia (LCD) was much more frequent in cirrhosis and in LCC than in normal liver. AFP was presented inside the LCD hepatocytes. These support the hypothesis that LCD may be precancerous lesion of LCC. Statistic analysis of immunohistochemical stains in 76 cirrhosis cases showed that the occurence of LCD was closely related to hepatitis B but not schistosomiasis.
出处
《湖南医科大学学报》
CSCD
1989年第1期17-20,共4页
Bulletin of Hunan Medical University
关键词
LCD
肝癌
肝硬变
HBSAG
HBCAG
liver cell dysplasia
liver neoplasms
liver cirrhosis
hepatitis B surface antigens
hepatitis B core antigens
pathology
