保定市618例腹泻病原菌分布与药敏

Distribution of dirarrhoea pathogen and identification of its drug-susceptibility(Report of 618 cases)

目的 研究保定市引起腹泻病原菌分布 ,为临床合理用药提供理论依据。方法 从 2 0 0 0年 - 2 0 0 1年对保定市6 18例腹泻患者进行大便细菌培养及药敏实验。结果 细菌培养阳性 2 15例 ,检出率 40 .5 % ,共 9个菌属。其中志贺氏菌属 112例 (4 4.6 % ) ;致病大肠杆菌 48例 (19.1% ) ;沙门氏菌属 43例 (17.2 % ) ,其次为不凝集弧菌、变形杆菌等。结论 致病大肠杆菌检出率明显增高 ,福氏志贺氏菌仍占优势 ,宋内氏志贺氏菌比例上升。 112例志贺氏菌药敏提示 :临床常用的抗菌素如庆大霉素、氨苄青霉素、氯霉素的敏感性明显降低 ,而丁胺卡那、氟哌酸。

Objective To study the bacterial distribution of diarrhoea in Baoding city and provide a proof for using medicine responsibly in clinical practice.Methods The bacteria were cultured in fresh stool collected from 618 patients in Baoding city from 2000 to 2001 and the bacterial drug susceptibility tests were taken at the same time.Results There were 215 positive examples and the detective rate was 40.5%.There were nine genus,among them,112 examples were Shrigella(44.6%);48 examples were EPEC(19.1%);43 examples were Salmonella(17.2%);others were Visrionaceae,Proteus and so on.Conclusion The rate of EPEC was significantly higher,S.flexneri still kept superiority.The rate of S.sonneis rose higher.The Shrigella drug-susceptibility tests of 112 examples showed that the sensitivity of antibiotics that often used in clinical practice such as Gentamicin,Ampicillin,Chloramphenicol was significantly reduced.Whereas the sensitivity of Kanamycin.Norfloxacin,Pipemidie Acid was more higher.