阴离子隙在多发性骨髓瘤诊疗中的意义

SIGNIFICANCE OF ANION GAP IN DIAGNOSIS TREATMENT OF MULTIPLE MYELOMA

用阴离子隙(AG)值分析多发性骨髓瘤(MM)的类型和疗效。39例患者中,IgG型23例,IgA型9例,其他7例。与对照组AG值比较,IgG型明显降低(P<0.01),IgA型明显升高(P<0.05),其他型无明显变化(P>0.05)。5例IgG型MM於治疗前AG值明显降低,而在有效治疗后恢复正常或接近正常。AG值的推算对IgG型和IgA型MM不仅有诊断价置,而且还能评价疗效。

Sixty-eight cases of multiple myeloma were admitted to our hospital from 1980-1989.Among them, the value of anion gap was calculated in 39 casses: which contain 23 cases of IgG type, 9 of IgA type and 7 of the other type.In comparison with the value of anion gap of control group, IgG type was significantly decreased (P<0.01), IgA type was significantly increased (P< 0.05) and the other type showed no significant difference (P>.05) .The value of anion gap of 5 cases of IgG type was significantly decreased before treatment but it recovered toward normal or almost normal levels after successful treatment.The value of anion gap calculation is not only of diagnostic significance but also of use for evaluating efficiency of treatment for IgG and IgA type of multiple myeloma.