血清IV型胶原测定在肝硬化诊断中的应用

The application of serum gluey IV in the diagnose of hepatocirrhosis

目的 :检测不同肝病患者的血清IV型胶原含量 ,以判断其在肝硬化诊断中的应用。方法 :用双抗夹心酶免疫法进行测定。结果 :在各种肝病中血清IV型胶原含量均有不同程度升高 ,其中5 8.3%的慢活肝、86 .4 %的肝硬化组血清IV型胶原含量明显升高 ,与正常对照组有显著性差异 (P<0 .0 1)。结论

Objective: To find a accessiorial diagnose of hepatocirrhosis we can determine the serum gluey IV inthe hepatis sufferers. Methods: Enzyme-linked Immuosorbant assays with two antibodies(ELISA) . Resulst: The content of serum gluey IV arises in every type of hepatis, 58.3% of actue or chronic hepatis and 86.4% of hepatocirrhosis are much higher than the normol group ( P <0.01). Conclusion : The serum gluey IV can be a good criterion in the diagnose of hepatocirrhosis.