摘要
本文用GC/NPD和GC/MSD的方法,对尿样中的麻醉镇痛剂羟甲左吗喃、氨苄度冷丁、环丁甲羟氢吗啡以及中枢神经刺激剂香草酰二乙胺等的母体药物及代谢产物进行了检测,建立了可靠、灵敏和快速测定麻醉镇痛剂的方法。
The method for the analysis of anileridine, levorphanol, nalbuphine and ethamivan in urine by means of GC/NPD and GC/MSD is described. TFAA and MSTFA- MBTFA have been used in this procedure for TFA and TMS derivatization. The parent forms and the metabolites of the four drugs can be found by GC/NPD screening and GC/MSD confirmation. The method is reliable ,fast and sensitive.
出处
《药学学报》
CAS
CSCD
北大核心
1991年第8期606-610,共5页
Acta Pharmaceutica Sinica
关键词
麻醉镇痛剂
中枢神经
药物
Narcotic analgesics
CNS- Stimulant
GC/NPD
GC/MSD
