食管癌外照射加高剂量腔内治疗疗效分析

Effect of external irradiation(EI) and high dose intracowity irradiation(ICI) in esophageal carsinoma.

目的 研究外照射加腔内放射治疗食管癌疗效。方法 1995年 1月～ 1996年 6月收治 6 0例食管癌随机分为两组 :30例用 8MV直线加速器X线外照射DT6 6 70Gy ;30例用 8MV直线加速器X线外照射DT6 0Gy,结束后 2周视残留病灶情况给予腔内放疗 5 10Gy/ 1 2次。结果 吞咽症状改善单放组70 % ,外照射加腔内放疗组 90 %。 1、3、5年生存率单放组分别为 43 3%、16 7%、6 7% ,外照射加腔内放疗组分别为 83 3%、40 %、2 6 7% ,生存率对比有显著性差异。结论 外照射加腔内放疗较单纯外照射生存率明显提高 (P <0 0 5 )。但要适当掌握剂量 ,选择好适应证尤为重要。

Objective To observe curative effect to esophageal carcinoma with EI and high dose ICI. Methods 60 patients with esophageal carcinoma admitted to the hospital in January, 1995 to June, 1996 were randomized divided to two groups. Thirty cases received X rays EI DT66～70Gy with 8MV linear ac-celerator; the other 30 cases received X rays EI DT60Gy with 8MV linear accelerator. After 2 weeks, ICI 5-10Gy/1-2 times was given according to surriring focus. Results Swallow symptom improved respectively 70%(in simple irradiation) and 90%(EI and ICI). Survival rates of 1?3?5 years were 43%?16.6% and 10%(in simple irradiation), 75%?33%?24%(in EI and ICI) respectively. Conclusion Survival rate can be improved obviously with EI and ICI.