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肽核酸及其类似物的合成方法概述 被引量：1

Synthetic methods of PNA and its analogs
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摘要 肽核酸 (PNA)作为一种反义核酸类化合物 ,在分子水平的疾病诊治上 ,有其独特的优越性 ,现在日益受到关注。综述了PNA类化合物的基本合成思路和几种主要合成方法 。 PNA,which is one kind of anti sense nucleic acid compounds,has its unique advantages in the molecular diagnostics and treatment of diseases.Now,people gradually attach more importance to PNA.This article reviewed the basic synthesis idea and several primary synthetic methods of PNA.It also included some specific synthetic methods of the PNA analogs.
作者 张婷 徐萍
机构地区 北京大学药学院药物化学系
出处 《中国药物化学杂志》 CAS CSCD 2002年第3期172-178,共7页 Chinese Journal of Medicinal Chemistry
基金 国家重点基础研究规化项目 (G19980 5 1114 )
关键词 肽核酸 肽核酸类似物 合成 PNA PNA analogs synthesis
分类号 R914 [医药卫生—药物化学]
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参考文献20

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同被引文献8

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中国药物化学杂志
2002年 第3期

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