第一极体位置对卵母细胞显微注射受精后受精和胚胎发育的影响

The Influence of the First Polar Body Position at Intracytoplasmic Sperm Injection on Fertilization and Embryo Development

目的 研究第一极体位置对卵母细胞显微注射受精后受精和胚胎发育的影响。方法 回顾分析了 782个经卵母细胞浆内单精子注射 (ICSI)的卵母细胞 ,分别分析第一极体位于 12点和 6点时的卵母细胞存活率、卵母细胞受精率和卵裂胚胎的发育质量。结果 第一极体位于 6点时的卵母细胞存活率、卵母细胞受精率、卵裂胚胎发育质量均略高于 12点位置 ,但差异均无显著性 (P >0 .0 5 )。结论 显微注射受精时的第一极体位置对卵母细胞的受精和胚胎发育的影响不大。

Objective To investigate the effect of the first polar body position during the intracytoplasmic sperm injection on fertilization and embryo development.Method A retrospective study on intracytoplasmic sperm injection (ICSI) of 782 oocytes was performed.The oocyte survival rate,normal fertilization rate and cleavage embryo quality were analyzed according to first polar body positioned at 12 o'clock or 6 o'clock.Result A little higher oocyte survival rate,normal fertilization rate and cleavage embryo quality were obtained when polar body positioned at 12 o'clock than 6 o'clock,but the difference was not significant.Conclusion The first polar body position does not significant influence the normal fertilization and embryo development.