枸橼酸铋雷尼替丁的临床应用进展

Ranitidine bismuth citrate (RBC):updated review

枸橼酸铋雷尼替丁 (RBC)是被众多国家批准的治疗消化性溃疡和根除幽门螺杆菌 (Hp)的新化合物。RBC具有抑制胃酸分泌、粘膜保护、根除Hp、抑制胃蛋白酶活性以及与抗菌药的协同作用 ,其与抗菌药联合使用根除Hp受耐药的影响小 ,并具有药物经济学价值 ,是目前国际消化界普遍推荐的根除Hp一线用药方案之一。

Ranitidine bismuth citrate(RBC) is a new chemical entity which has been approved in many countries as a therapy for peptic ulcer and recommended as one of the first line therapies for eradication of H.pylori (Hp) due to its characteristics of gastric acid inhibition,gastric mucosal protection,Hp suppressing,gastrin and pepsin inhibition and synergy with antibiotics.The eradication of Hp with RBC triple therapy don't be affected by the Hp strains which are resistant to antibiotics.\;[