桔梗提取工艺的研究

Studies on Extraction Process of Radix Platycodi

以桔梗中总皂甙含量和浸膏率为考察指标,应用正交设计优选桔梗的提取工艺,选择乙醇浓度、乙醇用量、提取次数和提取时间为影响因素,每个因素取三个水平。结果表明,最佳提取条件为:70％乙醇用最为药材量的3倍,回流提取 5次,每次60 min,优选得到的工艺稳定可行。

The orthogonal design was used to optimize the extraction process of Radix Platycodi with content of total saponin and yield of the extract as markers. Factors that have been chosen were alcohol concentration, alcohol consumption, extraction times and extraction time. Each factor has three levels. The result showed that the optimum extraction condition obtained was 70% alcohol, 3 times the amount of material , refluxing for 5 times, 60 minutes each time, the optimized process was stable and workable.