锡类散对溃疡性结肠炎患者血浆C反应蛋白含量的影响

Effect of Xileisan on C reactive protein in patients with ulcerative colitis

目的 探讨锡类散治疗前后溃性结肠炎患者血浆C反应蛋白 (CRP)水平的变化 ,并对其意义进行了探讨。方法 对40例溃疡性结肠炎患者及 2 0例对照者用C反应蛋白试剂盒进行血浆CRP检测。结果 溃疡性结肠炎活动期CRP活性显著高于对照组 (P <0 0 1) ,轻 ,中重度之间也存在显著差异 (P <0 0 1) ,经锡类散治疗后 ,CRP水平显著降低 ,与正常对照组间不存在显著差异(P >0 0 5 )。结论 C反应蛋白与溃疡性结肠炎的活动性相关 ,可提示病情的严重程度 ,锡类散对溃疡性结肠炎有显著疗效。

Aim To investigate the C reactive protein(CRP) in patients with ulcerative colitis (UC) before and after the treatment of Xileisan. Methods Forty cases of UC and 20 control cases were analysed using CRP detecting kit. Results In active phase of UC, CRP level was significantly higher than that in remission ( P <0.01), and it correlated significantly with the clinical grading of UC( P <0.01).After the treatment with Xileisan, CRP level of patients decreased and had no significant distinction with normal cases.( P >0.05). Conclusions CRP correlate significantly with the activity and clinical grading of UC.Xileisan is highly effective for UC patients.