CT介入靶位注射胶原酶治疗腰椎间盘突出症

TARGET-INJECTION OF COLLAGENASE BY CT INTERVENTION FOR THE TREATMENT OF LUMBAR DISC HERNIATION

目的:探讨CT介入靶位注射胶原酶治疗腰椎间盘突出症的临床应用价值。方法:198例接受注射胶原酶溶盘术的腰椎间盘突出症患者分为非CT组（100例）和CT组（98例）,非CT组依据腰椎CT片和腰椎定位片定位,凭经验操作;CT组在CT介入下定位和操作。结果:CT组的优良率和有效率分别为84.7％和94.9％,较非CT组分别提高了12.7％和8.9％,经X2检验,p值均<0.05。结论:CT介入下靶位注射胶原酶溶盘术,直观,安全,可提高术前诊断的准确性和术中穿刺的精确性,从而可提高临床疗效。

Objective: To evaluate the clinical efficacy of the target-injection of collagenase under CT intervention for the treatment of lumbar disc herniation. Methods: 198 patients with lumbar disc herniation at L4-5 or L5-S1 were included in this study. There were 100 cases in no-CT group and 98 cases in CT group. The operations were carried out respectively by experience in no-CT group and by CT intervention in CT group. Results:The excellent and good rate was increased from 72.0% (in group no-CT) to 84. 7% ( in group CT) ,P <0. 05 ; The effective rate was increased from 86. 0% to 94. 9% ,P <0. 05. Conclusion ; The target-injection of collagenase under CT intervention made the operation safer and easier to monitor. It can improve diagnosis before operation and make the puncture more precise. Therefore, it can improve the clinical curative effect.