卵巢透明细胞癌15例临床病理分析

Ovarian clear cell carcinoma: a report of 15 cases

目的 对 15例卵巢透明细胞癌进行分析 ,掌握其临床病理学特点。方法 研究 15例卵巢透明细胞癌临床与病理资料并随访总结发病规律与特点。结果 术后 11年、12年及 2 6年各 1例仍健在 (均为临床Ⅰ期 ) ;术后随访 5年及 2年 (临床Ⅱ期 )各 1例仍健在 ;2例分别生存 6年 (复发瘤切除 )及 7年 (临床Ⅱ期 )后死亡 ,7例 (临床Ⅲ～Ⅳ期 )于术后 10个月至 2年内死亡 ,失访 1例。结论 本癌预后与临床分期直接相关 ,与肿瘤体积、有 /无腹水、肿瘤扩散程度、肿瘤侵犯单侧或双侧卵巢等因素密切相关。

Objective To analyse the clinical and pathological characteristics of ovarian clear cell carcinoma for a better understanding and improvement of medical management of the tumor. Methods The clinical and pathological data were studied in 15 cases of ovarian clear cell carcinoma with follow-up. Results Three cases with clinical stageⅠwere still alive and in health for 11, 12 and 26 years after operation,respectively.In the patients followed up postoperatively, two case with clinical stage II were still alive for 5 and 2 years,respectively. Other two patients with clinical stageⅡdied of recurrent tumour 6 years and 7 years later. Seven cases with clinical Ⅲ and Ⅳ stages were all dead within 10 months to 2 year after operation. One case was failed to follow up. Conclusions The prognosis of ovarian clear cell carcinoma has a direct bearing on the clinical staging, and a close correlation with the bulk of tumours, presence of ascites, the degree of dissemination, invasion of one or both sides of the ovary and differentiation of the tumor cells.