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新的抗病毒药——咪喹莫特 被引量:5

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摘要 咪喹莫特(Imiquimod)属咪唑喹啉类化合物,为小分子免疫调节剂.美国FDA 1997年批准3M公司将5%咪喹莫特乳剂用于治疗外生殖器/肛周疣.生殖器疣(Genital Wart,GW)或尖锐湿疣(Condylomata Acuminata,CA)是由人乳头状瘤病毒(Human Papilloma Virus,HPV)引起的最常见性传播疾病(sexsual transmited diseases,STD)之一.
出处 《中国性病艾滋病防治》 2002年第3期187-190,共4页 Chinese Journal of Std & Aids Prevention and Control
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参考文献9

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  • 6Imbertson LM.Beaurline JM.Couture AM.et al.Cytokine inductionin hairless mouse and rat skin after topical application of the immune response modifiers Imiquimod and S - 28463[].Journal of Investigative Dermatology.1998
  • 7McDermott DJ . Senta TA. Smith MH. et al.Arising single dose safety,pharmacokinetical pharmacodynamic study of Imiquimod( AldaraTM) applied to the cervix of healthy female volunteers [poster][]..1999
  • 8Fleming DT.McQuillan GM.Johnson RE.et al.Herpes simplex virustype 2 in the United States 1976 to 1994[].The New England Journal of Medicine.1997
  • 9Miller RL. Imbertson LM.Reiter MJ.et al.Treatment of primary her-pes simplex virus infection in guinea pigs by imiquimod[].Antiviral Research.1999

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