感染性休克病人的血流动力学特点及意义

Significance of hemodynamic variables in patients with septic shock

目的 了解感染性休克病人早期血流动力学改变的特点及与预后关系。方法 临床前瞻性研究 ,监测感染性休克早期血流动力学改变并分析与预后的关系。结果 共连续观察 4 8例病人 ,其中 2 5例(5 2 % )死亡。一些指标的水平在死亡者与生存者间差别较大 ,其中包括平均肺动脉压 (MPAP)、肺动脉楔压 (PAWP)、体 /肺循环阻力指数 (SVRI/PVRI)、左 /右心做功 (LCW/RCW )和左 /右心每搏动 (LCSW/RCSW)等血流动力学指标和氧合指数、动脉混合静脉血含氧量差 (a vDO2 )、全身性炎症反应综合征(SIRS)指标积分等。结论 感染性休克病情凶险 。

Objective Investigation of the prognostic significance of hemodynamic variables in patients with septic shock.Methods Observation of ICU patients with septic shock for a 28 day interval.Results 25 of the 48 patients died(mortality rate 52%),most of those in a week.Levels of some hemodynamic variables such as MPAP,PCWP,LCW,RCW,LVSW,RVSW and other parameters such as Horovitzs quotient,a vDO 2,SIRS score differ greatly between the survival and the non survival.Conclusion Some hemodynamic variables are valuable in predicting survival of septic patients. [