医院获得性肺炎4种治疗方案的成本-效果分析

The Cost-effectiveness Analysis of Four Therapeutic Schemes for Nosocomial Pulmonary Infections

目的 :评价4种治疗方案的药物经济学效果。方法 :运用成本 -效果分析法对4种治疗方案进行分析。结果 :头孢曲松、亚胺培南的成本 -效果比基本相当 ,较头孢呋辛与庆大霉素联合用药的成本 -效果比低 ;头孢曲松成本较低 ,而亚胺培南治愈率及总有效率最高 ;哌拉西林与丁胺卡那联合用药的成本最低 ,但治愈率和有效率亦低。结论 :药物经济学在优化治疗方案、指导合理用药。

OBJECTIVE:To evaluate the pharmacoeconomic effectiveness of four therapeutic schemes METHODS:By using cost-effectiveness analysis,four therapeutic schemes for nosocomial pulmonary infections were analysed RESULTS:The cost-effectiveness ratio of ceftriaxone and imipenem was lower than that of cefuroxime and gentamycin The cost of ceftriaxone was low and imipenem had the highest curative rate and total effective rate The cost-effectiveness ratio of piperacillin and amikacin was the lowest,but the curative rate and effective rate of them were the lowest too CONCLUSION:Pharmacoeconomics plays an important role in optimizing therapeutic scheme,guiding rational use of drug and rising the economic benefit