野蔷薇根的化学成分研究

Studies on the Constituents of Rosa multiflora Thunb

目的 对野蔷薇根的化学成分进行研究。方法 采用乙醇提取、溶剂萃取、柱层析、重结晶等方法从蔷薇科植物野蔷薇的根中提取分离活性成分 ,通过波谱方法进行结构鉴定。结果 自野蔷薇根的醇提物中分得 7个化合物。结论 除文献报道过的野鸦春酸 (euscaphicacid) (3) ,sericicacid(4) ,kaji ichigosideF1(5 ) ,野蔷薇甙 (rosamultin) (6 )和niga ichigosideF2 (7) ,还首次从野蔷薇根中分到fupanzicacid(1) ,2 oxo pomolicacid(2 )。

AIM\ Bioactive constituents were expected to obtain from \%Rosa multiflora\% Thunb.. METHODS\ It was extracted with ethanol, distributed by different solvents, isolated and purified via column chromatography on silica gel, and MCI gel and Rp 18 gel, structures were elucidated based on spectral evidences. RESULTS\ A chemical study on the whole plant of \%Rosa multiflora\% was carried out, and seven compounds were isolated and identified as Fupanzic acid (1)?2 oxo pomolic acid (2)?euscaphic acid (3)?2α,3α,19α,24 tetrahydroxyolean 12 en 28 oic acid (4)? kaji ichigoside F 1 (5)? rosamutin (6), and niga ichigosides F 2 (7). CONCLUSION Fupanzic acid (1) and 2 oxo pomolic acid (2) were isolated from \%Rosa multiflora\% for the first time.