高海拔移居低海拔人群与世居低海拔人群高血压相关疾病调查对比分析

Reserch of related diseases of hypertension between persons who migrated from high-altitude and lived at low-altitude all the time

目的 :探讨高海拔移居低海拔人群与世居低海拔人群高血压相关疾病发生率的异同。方法 :调查从西藏高原 (海拔 30 0 0米以上 )移居四川省成都市且住地相对集中的汉族人群罹患高血压者 10 8例为研究对象 ,世居成都市人群罹患高血压 12 1例为对照组 :通过询问病史、查体和采集空腹静脉血测定血糖、血脂、血尿酸以及心电检查或选择性冠脉造影、脑CT(或MRI) ,就两组高血压相关疾病发生率进行比较 ,所有数据采用卡方检验 ,P≤ 0 .0 5表示有显著性差异。结果 :高血压相关疾病中糖尿病、脂代谢异常、高尿酸血症、冠心病及脑卒中两组差异均无显著性 (P >0 .0 5 )。结论 :高海拔移居低海拔人群高血压各相关疾病患病率与世居低海拔人群接近 。

Objective:Explore the difference of incidence of related diseases of hypertension between people who migrated from high-altitude and who lived at low-altitude all the time. Methods:Investigated 108 cases of Han persons who have hypertension and who migrated from Tibetan Highland (altitude above 3000m)to Chengdu of Sichuan Provincu. 121 cases of hypertension patients who have lived in Chengdu all their lives were used as contrastive grorp.Compared the incidence of related diseases of hypertension of these two groups by asking case history,examining body,collectiong veined blood on an empty stomach to determine blood glucose,blood-fat and blood acid uric and checking electrocardiogram of selective corono-angiography or brain CT(or MRI).All data use Chi-square test P≤0.05means remarkable difference. Results:Among related diseases of hypertension,diabetes,abnormal of lipoid metabolism,hyperuric acidemia,coronary heart disease and apoplexy,all show no apparent difference in both groups(P<0.05)? Conclusion:The incidence of having each related diseases of hypertension is close between persons who lived at low-altitude all their lives and those who migrated from high-altitude.Therefore,the prevention and cure work of related diseases of hypertension of persosns who migrated from high-altitude must be cared equally as that of those who lived all their lives at low-altitude.