扩张型心肌病患者甲状腺素水平变化及临床意义

The clinical significance on the change of thyroxine in the patients with dilated cardiomyopathy

目的 探讨扩张型心肌病患者甲状腺素水平变化的临床意义。 方法 纠正心衰的同时加甲状腺素 5mg 天 ,用放射免疫法测定治疗前后TT3、TT4 、FT3、FT4 、TSH ,同时用超声心动图测定扩张型心肌病患者治疗前后的左室射血分数。 结果 治疗前TT3为 0 70nmol L± 0 32nmol L ,显著低于对照组的 2 32nmol L± 1 15nmol L ,加用甲状腺素 5mg 天治疗后为 2 12nmol L± 0 92nmol L。左室射血分数治疗前为 0 2 5± 0 0 2 ,治疗后为 0 4 9± 0 0 4。 结论 扩张型心肌病的严重程度与甲状腺素的水平密切相关。

Objective To investigate clinial significance on the change of thyroxine in the patients with dilated cardiomyopathy Methods The thyroxine(5mg/day) during treating cardiac insufficiency,was used Before and after treatment,TT 3?TT 4?FT 3?FT 4?TSH were detected with radioimmunoassay and left ventricular ejection fraction with echocardiogram Results Before treatment,TT 3 was 0 70nmol/L±0 32nmol/L,and less than control group(2 32nmol/L±1 15nmol/L),the left ventricular ejection fraction was 0 25±0 02; After treatment TT 3 was 2 12nmol/L±0 92nmol/L;and left ventricular ejection fraction was 0 49±0 04 Conclusion The order of severity on dilated cardiomypathy is bound up with the level of thyroxine