老年冠心病患者冠状动脉病变特点及其危险因素的多元回归分析

Analysis of the angiographic features and the cardiovascular risk factors in elderly patients with coronary heart disease

目的 用冠状动脉造影技术研究老年冠心病 (CHD)患者冠状动脉病变特点和危险因素对其的影响。 方法 将 12 8例CHD患者根据其年龄分 2组 ,老年组 6 7例 ,非老年组 6 1例。均详细询问有无CHD的危险因素并做左右冠状动脉造影。对危险因素做Logistic多元回归分析。 结果 老年组冠状动脉病变大部分为多支病变 ,2支和 3支病变占 76 1% ,狭窄程度 99%以上者占 5 9 7% ;非老年组以单支病变为主 ,占 5 4 1% ,狭窄程度轻重均匀分布。Logistic多元回归分析显示危险因素在老年组与非老年组有不同影响的是性别、高胆固醇血症、家族史和年龄 (均为P <0 0 1)。 结论 老年CHD患者冠状动脉以多支病变为主 ,狭窄程度大多较重 ;性别、高胆固醇血症、年龄、CHD家族史和高血压是影响老年人CHD发病的相关危险因素。

Objective To assess the correlation of the characteristics of coronary lesion and the risk factors to the coronary heart diseases using angiography techniques. Methods Coronary heart disease (CHD) patients were divided into two groups according to the ages of patients: elderly group (67 cases, 60 88 years); non elderly group(61 cases, 25 59 yeas). Angiography was performed in all CHD patients and their risk factors were analyzed by Logistic regression. Results The coronary changes were characterized in most patients by multi vessels lesion(76 1%) in elderly group, while by single vessel lesion (54 1%) in non elderly group. Stenosis of the coronary artery in the elderly group was severer than that in the non elderly. Logistic regression showed that ageing, sex, hyperlipemia were the risk factors for CHD( P <0 01). Conclusions Major angiographic features of CHD patients in the elderly group was multi vessels lesion with severer stenosis. Sex, hyperlipemia, aging, CHD family history and hypertention were related with CHD patients of the elderly group.