灯盏花注射液治疗冠心病的临床观察

Clinical Observation of Dengzhanhua Injection on Coronary Heart Disease

目的 :观察灯盏花注射液治疗冠心病的临床疗效。方法 :对60例冠心病患者 ,随机单盲分为治疗组30例 ,采用常规口服扩冠药加灯盏花注射液治疗 ;对照组30例 ,单用常规口服扩冠药。结果 :治疗组、对照组治疗冠心病的总有效率分别为83.3 %、53.3 % ,两组比较差异有显著性 (P<0.05) ;2组均可使超氧化物歧化酶(SOD)明显升高 ,脂质过氧化物 (LPO)明显降低 ,且两组比较差异有显著性 (P<0.05) ;2组心电图的总有效率分别为80.0 % ,53.3 % ,两组比较差异有显著性 (P<0.05) ;2组对血液流变学的影响的总有效率分别为86.7 %、63.3 % ,两组比较差异有显著性 (P<0.05)。结论 :加用灯盏花注射液治疗冠心病比单用常规口服扩冠药疗效更好。

Objective: To observe the clinical effect of Dengzhanhua Injection for treating coronary heart disease. Methods: Sixty patients were randomly and blindly assigned to receive routine oral dilational medicine for coronary artery plus Dengzhanhua Injection in treatment group (n=30) and dilational medicine alone in control group (n=30). Results: The total effective rates in treatment group and control group were 83.3% and 53.3% respectively with significant difference (P<0.05). Both of these two methods could markedly increase SOD and lower LPO in blood. Obvious difference was found between these two groups (P<0.05). For changes of ECG and blood rheology,the effective rates were 80%, 53.3% and 86.7%, 63.3% and the comparison of both parameters between two groups had significant difference (P<0.05). Conclusion: The therapeutic effect of combined use of Dengzhanhua Injection and routine administration of dilational medicine for coronary disease is better than that of the latter alone.