生长抑素在重症急性胰腺炎治疗中的临床观察

Clinical Observation of Somatostatin in the Treatment of Severe Acute Pancreatitis

目的 :探讨生长抑素在重症急性胰腺炎临床治疗中的作用。方法 :将 10 2例重症急性胰腺炎病人分为生长抑素治疗组 (n =5 2 )和对照组 (n =5 0 ) ,对两组之间胰腺囊肿、胰腺脓肿、胰瘘、肠瘘、腹腔内出血的发生率、病死率、死亡原因及住院天数进行了对比分析。结果 :生长抑素治疗组的并发症明显低于对照组 ,生长抑素可降低重症急性胰腺炎病人的病死率 ,缩短住院时间 ,而且生长抑素使用的早晚对重症急性胰腺炎病人的治疗也有重要的影响。结论 :生长抑素对重症急性胰腺炎的治疗有重要的价值 ,越早使用效果越好。

Objective: Our aim was to observe the effect of somatostatin on treatment of severe acute pancreatitis. Methods: We divided 102 cases of severe acute pancreatitis into somatostatin treating group (n=52) and control group (n= 50). Contrast analysis was made between the two groups on the mortality, death reason, and hospital stay of pancreatic cyst, pancreatic abscess, pancreatic fistula, bowel fistula, intraabdominal hemorrhage. Results: The complication rate of somatostatin treating group was obviously less than that of control group. Somatostatin could decrease the mortality of severe acute pancreatitis, shorten the hospital stay and the treating time. Somatostatin had important influence in the treatment of severe acute pancreatitis. Conclusion: Somatostatin has important value for the treatment of severe acute pancreatitis. The earlier we performance of the treatment, the better effect we would have.