生姜醇提物对荷瘤鼠免疫功能的影响

Effect of alcohol extract of Zingben officinale rose on immunologic function of mice with tumor

为了探讨生姜醇提物对荷瘤鼠免疫功能的影响 ,荷瘤鼠灌胃给药生姜醇提物 4 0g kg ,10g kg。以胸腺、脾脏的脏器指数、巨噬细胞吞噬率、α醋酸萘酯阳性率 (α -ANAE +)、溶血素 (IgM)为指标 ,研究生姜醇提物对非特异性免疫和特异性免疫功能的影响。结果发现 :生姜醇提物能明显升高脏器指数 ,提高荷瘤鼠巨噬细胞吞噬率 ,使荷瘤鼠α ANAE阳性率和IgM得以回升。

In order to study the effect of alcohol extract of Zingben officinzle rose on immunologic function of mice with tumor, mice are orally administrated with dose of 10g/kg and 40g/kg alcohol extract of Zingben officinale rose. The thymus index, spleen index, percentage of phagocytosis, rate of α-ANAE+ and level of hymolysin(IgM) are use in the study as the parameters to evaluate the effect of alcohol extract of Zingben officinale rose on non-specific and specific immune function of mice with tumor. The results indicate that alcohol extract of Zingben officinale rose can raise significantly the thymus index, spleen index, percentage of phagocytosis, rate of α-ANAE+and titer of IgM of mice with tumor indicating that alcohol extract of Zingben officinale rose can improve significantly the status immunologic function in mice.inadequacy of mice with tumor.