摘要
作者报告了红细胞磷酸丙糖异构酶测定法及中国人正常值。结果表明:中国人成年男性(24名)和女性(20名)此酶活性分别为1980±413EU/gHb和2130±543EU/gHb,无显著差异(P>0.2)。正常脐血19例测定结果为1840±658EU/gHb,与成年人无显著差异(P>0.2)。作者还对此酶缺乏的临床表现及遗传学作了讨论。
Hereditary erythrocyte triosephosphate isomerase(TP Ⅰ )deficiency was demonstrated to be one of the causes of non-spherocytic hemolytic aneamia, sometimes with multiple anomalies. A spectrophotomeric assay method was recommended to determine TP Ⅰ activity in erythrocytes. The normal value among healthy Chinese adults was obtained as 2048 ±471EU/gHb. Among new borns, the TP Ⅰ activity was found to be 1840 ± 658 EU/gHb. No significant difference was found between the two groups. The method was evaluated and its clinical application was also discussed.
出处
《遗传与疾病》
CSCD
北大核心
1991年第4期199-202,251,共4页
基金
国家计生委
自然科学基金
