脑转移瘤MRI误诊病理学分析

Pathological analysis of metastatic brain tumors misdiagnosed with MRI

目的 :分析脑转移瘤MRI误诊的病理学基础 ,为MRI诊断提供依据。方法 :对 7例误诊病例进行病理形态学观察、免疫组织化学检测及MRI影像学分析。结果 :7例误诊病例均为单发大结节病变 ,均有不同程度的出血、坏死 ,多数有囊性变、瘤周胶质细胞增生肥大 ,瘤内、瘤周微血管大量增生。结论 :脑转移瘤出现明显继发改变及瘤周反应是MRI误诊的根本原因 ,MRI图像不典型时 ,应结合其它方法和资料综合诊断。

Objective To study the pathological basis of metastatic brain tumors misdiagnosed with (MRI). Methods Seven cases were analyzed histopathologically and immunohistochemically, compared with the MRI image. Results All the tumors were single large noduls. Hemorrhage and necrosis of the tumors were seen in all the cases. Cystformation of the tumor, glial cell proliferation and vascular proliferation of peritumoral brain tissues were seen in most cases. Conclusion The secondary changes of metastatic brain tumors and the reactive changes of peritumoral brain tissues are the major causes of MRI misdiagnosis.