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感觉神经肽SP在伤口愈合细胞因子网络调控中的作用 被引量：7

Effects of neuropeptide substance P on cellular factor net in wound healing
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摘要 P物质 (SP)是介导机体创伤愈合神经调控的一种重要的感觉神经肽 ,对创伤愈合具有重要的作用 ,它通过促进创伤后的炎症反应、修复细胞的增殖和组织重建 ,从而作用于创伤愈合的各个环节。在这一过程中 ,SP与参与创伤愈合的细胞因子网络之间存在着复杂的交互作用。 Substance P, one of important neuropeptides, plays an important role in wound healing. The probable mechanism is that substance P takes effect on various wound healing through promoting inflammatory reaction,proliferation of repaired cells and tissue reconstruction. During the course, there are complicated and interchangeable effects between substance P and cytokine net, both cooperative effect and antagonizing effect. In the paper, we have reviewed the progress of research in recent years.
作者 蒋伟 王正国 赖西南
机构地区 第三军医大学野战外科研究所
出处 《创伤外科杂志》 2002年第4期250-252,共3页 Journal of Traumatic Surgery
基金 国家"973"重大课题资助项目 (G1999054205 )
关键词 感觉神经肽SP 伤口愈合 细胞因子 网络调控 作用 P物质 substance P wounds healing cytokines
分类号 R64 [医药卫生—外科学]
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参考文献21

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创伤外科杂志
2002年 第4期

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