裸花紫珠片的抗菌消炎和止血作用研究

Study on the Effects of Callicarpa nudiflora Tablets in the Antibiosis and Antiphlogosis and the Hemostasis

为考察裸花紫珠片的抗菌消炎、止血功效 ,用试管体外抗菌、毛细血管通透性、耳肿胀、跖肿胀、出凝血时间等方法对裸花紫珠片进行了药理研究 ,结果表明 :裸花紫珠片对金黄色葡萄球菌、伤寒沙门氏菌、肺炎球菌有不同程度的抑菌作用 ,对冰醋酸所致的小鼠腹部毛细血管通透性增加和二甲苯所致的小鼠耳肿胀具有非常显著的抑制作用 ,并明显抑制大鼠蛋清性足肿胀形成和缩短小鼠的出凝血时间 .

To investigate the efficiency of Callicarpa nudiflora tablets in the antibiosis and antiphlogosis and the hemostasis,the authors make a pharmacological study to it in these respects such as the antibiosis in vitro,the capillary permeability,the auricular tumefaction,the metatarsal tumefaction,the bleeding and blood clotting time etc..The results show that Callicarpa nudiflora tablets have the effects of different levels on Staphylococcus aureus, Salmonella typhosa,Diplococcus pneumoniae,and obviously inhibiting effects on the increase of mice's abdominal capillary permeability caused by glacial acetic acid and the mice's auricular tumefaction caused by dimethylbenzene;meanwhile it can obviously inhibit the rats' metatarsal tumefaction caused by albumen and decrease the bleeding and blood clotting time.All these indicate that Callicarpa nudiflora is a kind of antimicrobial and antiphlogistic drug which has widely pharmacological effects.