摘要
本文用循环伏安法研究了麦迪霉素推动质子从水相向硝基苯相或1,2-二氯乙烷相转移的过程,测定了麦迪霉素与质子在油相结合的稳定常数,建立了一种新的测定麦迪霉素的电化学方法。检测下限为10μg/mL,线性范围为20～1400μg/mL,样品检测结果与生物效价法相同。
Proton transfer across water/nitrobenzene and water/1,2-dichloroethane interfaces facili-tated by medemycin has been studied using cyclic voltammetry and can be used as a rapid,simple method for determination of medemycin over the range of 20～1400μg/mL. The detec-tion limit of medemycin is 10μg/mL. Drug samples were analyzed and compared withbiological assays with satisfactory results.
出处
《应用化学》
CAS
CSCD
北大核心
1991年第3期33-36,共4页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金
关键词
麦迪霉素
环循伏安法
抗生素
测定
cyclie voltammetry
medemycin
water/oil interface
