摘要
环糊精能在水溶液中包络尺寸合宜的分子至其疏水性的环状腔体中,包络过程被用于增大有机分子的水溶性,用作酶的模拟,用于色谱学、荧光光度法和室温磷光法等。β-环糊精(β-CD)是最通用的一种,其内腔直径为0.7nm。
The inclusion reactions of procaine, acetanilide and p-acetamidophenol with β-cyclodex-trin have been studied by means of absorption and fluorescence spectrometry and theirstability constants were calculated. Through inclusion, β-cyclodextrin enhances the fluores-cence emission of the drug molecules and, in particular, reduces the hydrolysis ofprocaine in aqueous solution.
出处
《应用化学》
CAS
CSCD
北大核心
1991年第4期80-82,共3页
Chinese Journal of Applied Chemistry
关键词
药物分子
Β-环糊精
络合
光谱
β-cyclodextrin
procaine
acetanilide
p-acetanidophenol
