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胸苷酸合酶与5-氟尿嘧啶耐药的关系 被引量:4

Relationship of thymidylate synthase and 5-fluorouracil resistance
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作者 卓丽娟
出处 《福建医科大学学报》 2002年第2期230-231,238,共3页 Journal of Fujian Medical University
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  • 1Seifert P,Baker LH,Reed ML,et al. Comparison of continusly infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma[J]. Cancer, 1975,36(1):123~128.
  • 2Hori T,Takahashi E,Ayusawa D,et al. Regional assignment of the human thymidylate synthase(TS) gene to chromosome band 18p11.32 by non-isotopic in situ hybridization[J]. Hum Genet, 1990,85(3):576~580.
  • 3Lenz HJ,Leichman CG,Danenberg KD,et al. Thymidylate synthase mRNA level in adenocarcinoma of the stomach:a predictor for primary tumor response and overall survival[J]. J Clin Oncol, 1996,14(1):176~182.
  • 4Yeh KH,Shun CT,Chen CL,et al. High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy[J]. Cancer, 1998,82(9):1626~1631.
  • 5Johnston PG,Lenz HJ,Leichman CG,et al. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors[J]. Cancer Res, 1995,55(7):1407~1412.
  • 6Davies MM,Johnston PG,Kaur S,et al. Colorectal liver metastasis thymidylate synthase staining correlates with response to hepatic arterial floxuridine[J]. Clin Cancer Res, 1999,5(2):325~328.
  • 7Bathe OF,Franceschi D,Livingstone AS,et al. Increased thymidylate synthasegene expression in liver metastases from colorectal carcinoma:implication for chemotherapeutic options and surviral[J]. Cancer J Sci Am, 1999,5(1):34~40.
  • 8Leichman L,Lenz HJ,Leichman CG,et al. Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers:preliminary report from an ongoing trial[J]. Eur J Cancer, 1995,31A(7,8):1306~1310.
  • 9Leichman CG. Thymidylate synthase as a predictor of response[J]. Oncology Huntingt, 1998,12(8 Suppl 6):43~47.
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