阻塞性睡眠呼吸暂停综合征患者上呼吸道的CT研究

The upper airway CT scan in patients with obstructive sleep apnea syndrome

目的 :探讨阻塞性睡眠呼吸暂停综合征 (OSAS)患者和正常人的上呼吸道CT资料的差异。方法 :对经多导睡眠监测 (PSG)确诊的OSAS患者和年龄性别相近的正常成年人各 5 3例 ,采用螺旋CT对上呼吸道进行连续扫描 ,测量并比较两组间有关数据。结果 :OSAS组软腭后区、悬雍垂区和舌后区的横截面积均明显小于对照组 ;左右径在所测量的 4个平面中均明显短于对照组 ;而前后径的比较除悬雍垂区以外 ,两组间差异均不明显 ;前后径 /左右径比值在会厌后区差异不显著 ,其余 3个区域差异明显 ;咽后壁的软组织厚度比较软腭后区和悬雍垂区差异明显 ,咽侧壁的软组织厚度比较 ,4个测量平面差异均显著 ,软腭后区咽侧脂肪面积比较差异不显著。结论 :上呼吸道的解剖性狭窄是OSAS的主要发病原因之一 。

Objective:To compare the CT scan results in OSAS patients and normal adults so as to explore its value in measuring upper airway structure. Method: 53 patients with OSAS and 53 normal adults were included in the study.The upper airway from roof of nasopharynx to glottis was evaluated with the use of a Phlips Tomoscan AV Expander E1 spiral scanner. The area and the dimensions of palate, uvula, lingua and epiglottis region was studied, and the thickness of retropharyngeal and lateral pharyngeal tissue were evaluated,too. Result:There were obviously differences between OSAS patients and normal adults in the areas of palate, uvula, lingua, and there are differences of dimension and thickness in different sites.Conclusion:The study suggests that there is a obviously difference between the patients with OSAS and normal adult in upper airway by CT scan.The anatomic structure of upper airway is one of causes of OSAS.