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β-淀粉样肽的结构、合成与性质及其与老年痴呆症的关系 被引量:3

β-Amyloid Peptide and Alzheimers′Disease
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摘要 β 淀粉样肽是 β 淀粉样前体蛋白的剪切产物 ,分别由 3 9~ 43个氨基酸残基组成。本文介绍了 β 淀粉样肽的化学结构、化学合成及 β 淀粉样肽与老年痴呆症的关系。 amyloid peptide (Aβ or βA) is produced by cleavage from β amyloid precursor protein(APP).Aβ is composed of 39~43 amino acid residues respectively.It is related to Alzheimer′s disease (AD).This paper is focused on the chemical structure,synthesis of Aβ and the relationship between Aβ and AD.
作者 刘勉 叶蕴华
出处 《化学通报》 CAS CSCD 北大核心 2002年第7期458-462,共5页 Chemistry
基金 国家自然科学基金资助项目 (2 9772 0 0 1)
关键词 结构 合成 性质 老年痴呆症 Β-淀粉样肽 Β-淀粉样前体蛋白 病因 治疗 Alzheimer′s disease, β Amyloid peptide, β Amyloid precursor protein
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同被引文献31

  • 1谢朝阳,梅寒芳,祝其锋.β淀粉样肽_(25-35)对PC细胞p53和bcl-2基因表达的影响[J].广东医学院学报,2005,23(2):121-124. 被引量:1
  • 2吴剑浩.从《伤寒论》抵当汤谈老年痴呆症从络病论治[J].中医杂志,2007,48(7):657-659. 被引量:11
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