萘磺酸盐与β-环糊精衍生物的包结行为

Inclusion Behaviors of Naphthalenesulfonate with β-yclodextrin Derivative

以自组装方式在石英晶体谐振器的金电极表面修饰末端含巯基的β-环糊精衍生物(β-CDd),用石英晶体微天平(QCM)在线监测α-、β-萘磺酸盐与之发生包结反应的过程,探讨了温度、浓度、取代基位置对包结反应稳定常数Kin和速率常数ka的影响.从理论上推导并通过实验验证了Kin和ka所遵从的关系式.结果表明:所形成的包结配合物中β-CDd与萘磺酸盐的化学计量均为1:1;包结配位反应过程符合Langmuir吸附模型;取代基在萘环上的位置对Kin和ka有很大影响,说明不同取代位置的萘磺酸盐与β-CDd的包结行为存在明显差异.

The thiol terminated β cyclodextrin derivative(β CDd) was attached to the surface of gold electrode of quartz crystal resonator by self assembly. The inclusion reactions of α naphthalenesulfonate and β naphthalenesulfonate with β CDd were monitored in situ by using quartz crystal microbalance (QCM). The influences of temperature, concentration, and the substituting position on naphthalene nucleus on the inclusion constant(Kin) and the rate constant(ka) were investigated. The relational expressions of Kin and ka were deduced theoretically and were testified by experimental results. The results obtained indicated that the stoichiometry of the inclusion complexes formed is 1:1 for the host β CDd with naphthalenesulfonate, that the inclusion reactions tallied the Langmuir adsorption model, that the substituting position on naphthalene nucleus has great effect on Kin and ka , and that the inclusion behaviors of the two derivatives with substituent at different positions with β CDd show obvious difference.