相转移催化(PTC)合成β-[2′-降冰片-5′-烯]α,β不饱和酮、醛类

Study on the Synthesis of β-(2'-norbornene-5'-yl)α,β-Unsaturated Ketones and Aldehydes in the presence of Phase Transfer Catalyst(PTC)

某些α,β不饱和酮、醛类化合物具有浓郁的果香,木香味,广泛存在于天然的精油、水果、蔬菜中,也是重要的有机合成中间体。对于它们的合成近来有不少报道。如β-[2′-降冰片-5′-烯]α。

Syntheses of β-(2'-norbornene-5'-yl)α,β-unsaturated ketones and aldehydes by the condensation of norbornene-5-carboxaldehyde-2 with appropriate aliphatic ketones and aldehydes in the presence of PTC have been studied 18-crown-6,quaternary ammonium salts andPEG showed good catalytic activity in the present specific cases.The prepared α,β-unsatura-ted ketones and aldehydes are found to be potencial perfume compounds.