血清肌钙蛋白T和心肌酶对心肌炎的诊断价值

Diagnostic value of cardiac troponin T and myocardium enzyme in myocarditis

目的:探讨肌钙蛋白T(cTnT)诊断VMC的价值。方法:对34例心肌活检的VMC患者和25例健康对照组进行cTnT,CK,CK-MB检测。结果:(1)VMC患者检出:①电镜阳性率100%(34/34);②光镜阳性率58.8%(20/34);③cTnT阳性率97.1%(33/34);④CK-MB阳性率41.2%;⑤CK阳性率11.8%;(2)心肌炎心功能Ⅲ级患者的cTnT,CK,CK-MB水平均高于Ⅱ级(P<0.001);(3)心肌炎病理变化与cTnT水平密切相关。结论:cTnT(≥0.12μg/L)是判断VMC患者心肌损伤的最佳指标。

ve: To explore the diagnostic value of cardiac troponin T and myocardium enzyme in myocarditis. Methods: Levels of cTnT. CK, CK-MB were detected in 34 patients with VMC diagnosed by biopsy and 25 normal control cases. Results: (1) VMC Positive rate of electron microscope detecting, optical microscope detecting, cTnT, CK-MB, CK was 100% (34/34). 58.8% (20/34), 97.1% (33/34), 41.2%. 11. 8% respectively; (2) Levels of cTnT, CK. CK-MB in VMC patients with MYHA heart function of Ⅲ grade higher than those of grade Ⅱ; (3)There was correlation between pathologic change and level of cTnT. Conclusion: Level of cTnT (≥0. 12μg/L) is best index of diagnose VMC.