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X-连锁和双基因型视网膜色素变性的相关基因研究进展 被引量：2

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摘要 视网膜色素变性 (retinitis pigmentosa,RP)是一组进行性、可致盲的单基因遗传性视网膜疾病 ,以视网膜光感受器和色素上皮功能进行性受损为主要特征。X-连锁 RP和双基因型 RP是视网膜色素变性的不同类型 ,在遗传和临床上各具特点。目前 ,X-连锁 RP已定位 6个致病基因 ,并克隆了 2个基因 (RP2和 RP3) ;双基因型 RP是由 2种不同基因(peripherin/ RDS和 ROM1基因 )
作者 邓新国 胡世兴
机构地区 中山大学中山眼科中心遗传及分子生物学实验室
出处 《眼科新进展》 CAS 2002年第3期209-211,共3页 Recent Advances in Ophthalmology
基金 美国纽约 CMB基金资助 (编号 :98-677)~~
关键词 视网膜色素变性 X-连锁RP 双基因型RP 致病基因 RP
分类号 R774.1 [医药卫生—眼科]
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参考文献35

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共引文献1

同被引文献21

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眼科新进展
2002年 第3期

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