提插、捻转法针刺足三里对新西兰兔胃电和血浆胃泌素、cAMP、cGMP的影响

Effects of Puncturing Zusanli (ST36) by Lifting and Thrusting and Rotating Techniques on Electrogastrogram and Plasma Levels of Gastrin,cAMP and cGMP in New Zealand Rabbits

[目的]观察提插法、捻转法针刺足三里穴对新西兰兔胃电、血浆胃泌素、环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)的影响。[方法]将30只新西兰兔分为提插和捻转两组,针刺前后分别记录体表胃电图,采用放射免疫分析法测定血浆胃泌素、cAMP和cGMP的含量。[结果]与捻转法相比较,提插法可升高健康新西兰兔胃电幅值并使频率增快(P<0.01或 P<0.05);提插法可升高血浆胃泌素及cAMP含量(P<0.05),但两种手法对血浆cGMP含量均无明显影响(P>0.05)。[结论]提插手法针刺足三里穴对新西兰兔胃电活动、血浆胃泌素、cAMP的作用比捻转手法强。

[Objective] To observe the effects of puncturing Zusanli (ST36) by lifting and thrusting and rotating techniques on electrogastrogram and plasma levels of gastrin, cyclic adenosine monophosphate (cAMP) and cyclic guanine monophosphate (cGMP) in New Zealand rabbits. [Methods] Thirty rabbits were allocated to two groups: Group A treated with lifting and thrusting techniques and Group B with rotating techniques. Body surface electrogastrogram was recorded and plasma levels of gastrin, cAMP and cGMP were examined by radioimmunological assay before and after treatment. [Results] As compared with Group B, the amplitude and frequency of electrogastrogram were elevated and the plasma level of gastrin and cAMP were increased in Group A ( P <0.01 or P <0.05). The difference of cGMP between two groups was not significant ( P > 0.05). [ Conclusion ] The effects of acupuncturing Zusanli (ST36) by lifting and thrusting techniques on electrogastrogram and plasma levels of gastrin and cAMP in New Zealand rabbits are stronger than those by rotating techniques.