摘要
目的 :探讨治疗非霍奇金淋巴瘤联合化疗最佳方案及用药合理性。方法 :根据文献选择 68例患者 ,随机分为 3组 ,分别给予以吡喃阿霉素 (THP)、表阿霉素 (E ADM)、阿霉素 (ADM)为主的联合化疗方案 ,运用药物经济学成本 效果分析方法进行评价。结果 :3组不同化疗方案中完全缓解率 (CR %)以E ADM组最高 ,不良反应发生总例次THP组最低 ,心脏毒性及脱发 3组间差异有显著性。结论 :应根据患者体质、经济条件等具体情况 。
Objective:To evaluate the combined chemotherapeutic schemes for optimum treatment of NHL and explore the rational use of drugs. Methods:A total of 68 patients were selected and randomly divided into three group, then the combined chemotherapeutic schemes with THP, E ADM and ADM were employed for treatment of the patients. Evaluation was made by use of phamacoeconomic cost effect analysis. Results:Among the three different chemotheraputic schemes, E ADM group is the best for complete relief, THP caused least adverse reactions among the total cases. Significant difference was found among the three group with regard to heat toxicity and trichomadesis caused. Conclusion:Clinicians should make suitable prescriptions in accordance with the patient's physical, financial and other speicific conditions.
出处
《医药导报》
CAS
2002年第7期443-445,共3页
Herald of Medicine
