低分子肝素钠引起上消化道出血一例

1 case of the dalteparin sodium induced upper gastrointestinal hemorrhage

[背景 ]低分子肝素钠对不稳定型心绞痛有明显疗效 ,且副作用小、安全 ,不需要凝血酶原时间、凝血酶时间及抗凝血酶时间等的检测 .[病例报告 ]以阵发性心前区针刺样疼痛为主诉而入院的老年患者 1例 ,临床诊断为不稳定型心绞痛 ,用低分子肝素钠治疗后出现上消化道出血症状 ,且其凝血酶原时间明显延长 .[讨论 ]低分子肝素钠虽然副作用小、安全 ,但应用时应进行凝血酶原时间、凝血酶时间及抗凝血酶时间等的检测 .

BACKGROUND?The dalteparin sodium has curative effect for the unstable angina pectoris, a few of side effects and safety, and has no specially need to detection for the prothrombin time, thrombin time, antithrombin time, and so on.?CASE REPORT?A senile patient with paroxysmal precordial stabbing pain administered in hospital was diagnosed for unstable angina pectoris, complicated with upper gastrointestinal hemorrhage after treatment with the dalteparin sodium some days later and the plasma prothrombin time was obviously prolonged.?DISCUSSION?Although the dalteparin sodium has a few of side effects and safety, but it must be detected at administration that the plasma prothrombin time, thrombin time, antithrombin time, and so on.