常规与节段性栓塞化疗在小肝癌治疗中的比较研究(附56例报告)

A Comparison between TOCE and S-TOCE in Treatment of Small Liver Carcinoma (A Report of 56 Cases)

目的 探讨常规栓塞化疗 (TOCE)与节段性栓塞化疗 (S TOCE)在小肝癌治疗中的疗效比较。方法 5 6例中2 6例行TOCE治疗 42次 ,平均 1.6次 /例 ,3 0例行S TOCE治疗 3 9次 ,平均 1.3次 /例。术后随访 6～ 3 6个月以上 ,并行B超、螺旋CT(SCT)及DSA (再次治疗时 )检查 ,以判断疗效。结果 2 6例行TOCE治疗病例 ,碘油完全充填 12例 ,占46.2 % ,-年内复发 5例 ,占 19.2 % ;3 0例行S TOCE治疗病人 ,碘油完全充填 2 5例 ,占 83 .3 % ,一年内复发 2例占 6.7% ;TOCE与S TOCE在小肝癌治疗中完全充填及术后复发等比较有显著差异 (P <0 .0 1)。结论 S TOCE是小肝癌非手术治疗首选方法。

Objective To compare the therapeutic efficacy of TOCE and S TOCE in treatment of small liver carcinoma. Methods Among the 56 cases, 26 received TOCE 42 times (mean=1.6 times/case) and the other 30 underwent S TOCE for 39 times (mean=1.3 times/case). After the treatments, all the patients were examined with B mode ultrasonography, spiral CT (SCT) and DSA (upon the re treatment) and followed for 6-36 months for judgment of therapeutic efficacy. Results For the 26 cases receiving TOCE, complete filling in the lesions by lipoiodol was found in 12 cases(46.2%) and recurrence of the carcinoma in 5 cases(19.2%) within 1 year. As for the other 30 cases receiving S TOCE, the complete filling by lipoiodol was found in 25 cases(83.3%) and recurrence of the carcinomas were only in 2 cases(6.7%) within 1 year. There were significant differences between the two groups of the patients ( P <0.01). Conclusion S TOCE should be the first choice for non surgical treatment of small liver carcinomas and its therapeutic efficacy is significantly better than that of TOCE.