颊粘膜替代阴茎白膜治疗Peyronie病(附14例报告)

Autologous buccal mucosal patch grafting in the surgical treatment of Peyronie's disease

目的 评价阴茎硬结切除后颊粘膜替代治疗Peyronie病的手术效果。 方法 Pey ronie病患者 14例 ,均行保守治疗无效 ,痛性勃起伴弯曲畸形 3个月以上 ,采用手术切除阴茎白膜硬结 ,自体颊粘膜替代治疗。 结果 随访 6～ 2 4个月 ,患者无阴茎缩窄致凹痕感 ,阴茎长度手术前后无变化 ,12例阴茎伸直 ;2例阴茎稍弯曲 (<15°) ;2例出现阴茎局部皮肤麻木 ;2例仍有痛性勃起。手术满意率 86 % (12 / 14)。 结论 颊粘膜在解剖和功能上与白膜相近 ,可作为手术切除阴茎白膜硬结后的理想替代材料。

Objective To evaluate autologous buccal mucosal patch grafting for correcting penile deformity in the surgical treatment of Peyronie's disease. Methods 14 patients with symptoms of Peyronie's disease for more than three months suffered from persistent pain ,severe curvature of the penile shaft and resistant to conservative treatment underwent plaque incision and autologous buccal mucosa patch grafting. Results Postoperative follow up has been 0.5 to 2years.The penile shaft became straight with no narrowing or indentation in 12 patients (86%) . In 14% of cases (2/14) some curvature of the penile shaft persisted and there was pain on erection.In all the patients there was no change in penile length. 86% of patients had overall satisfaction after surgery with improvement in psychological and social well-being. Conclusions The autologous buccal mucosal patch graft provides an anatomical and functional tunied substitute resulting in correction of the penile deformity in Peyronie's disease.