复发性脑梗塞事件相关电位研究

Event-related potentials in recurrent cerebral infarction

目的 探讨事件相关电位对复发性脑梗塞患者认知功能障碍的诊断价值。方法 对2 8例复发性脑梗塞患者进行事件相关电位检测并与对照组比较。结果 复发性脑梗塞组事件相关电位的N2、P3潜伏期与对照组比较显著延长 (P <0 .0 0 1) ,而且 18例MMSE >17分的复发性脑梗塞患者中 7例事件相关电位的P3潜伏期延长。结论 检测事件相关电位是评定复发性脑梗塞患者认知功能障碍的一种敏感。

Objectives To investigate the diagnostic value of event related potentials for cognitive impairment of patients with recurrent cerebral infarction.Methods An auditory event related potential was recorded from 28 patients with recurrent cerebral infarction as compared with age matched controls.Results The latencies of N2,P3 in the patients with recurrent cerebral infarction were significantly prolonged( P <0.001)as compared with controls, and the latencies of P3 were prolonged in 7 out of 18 cases that whose scores of MMSE were above 17.Conclusion Event related potential test provides a sensitive and objective means of quantifying the level of cognitive impairment for the patients with recurrent cerebral infarction.